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Network Biology, 2015, 5(2): 62-70
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Article

Implementation of fuzzy system using different voltages of OTA for JNK pathway leading to cell survival/ death

Shruti Jain1, D.S. Chauhan2
1Department of Electronics and Communication Engineering, Jaypee University of Information Technology, Waknaghat, Solan, Himachal Pradesh 173234. India
2GLA University, Mathura, Uttar Pradesh, 281406. India

Received 5 December 2014;Accepted 13 January 2015;Published online 1 June 2015
IAEES

Abstract
In this paper a well defined method for the design of JNK pathway for epidermal growth factor/ insulin using fuzzy system using operational transconductance amplifier was discussed. Fuzzy system includes fuzzification of the input variables, application of the fuzzy operator (AND or OR) in the antecedent, implication from the antecedent to the consequent, aggregation of the consequents across the rules, and defuzzfication. Fuzzy system with various electrical parameters for different voltages of OTA with different membership function was found. Results with 3V were the best.

Keywords epidermal growth factor (EGF)/ insulin;Jun N-terminal kinases (JNK);operational transconductance amplifier;fuzzy system;electrical parameters.


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