Birinchi Kumar Boruah Tazid Ali Department of Mathematics, Dibrugarh University, Assam 786004, India Network Biology ISSN 2220-8879 http://www.iaees.org/publications/journals/nb/online-version.asp 2022 12 1 1 10 International Academy of Ecology and Environmental Sciences Hong Kong 20 September 2021 30 October 2021 1 March 2022 genetic code amino acid mutation total graph Suppose R be a commutative ring and Z(R) its set of zero-divisors. Total graph is the (undirected) graph where set of all elements of R is taken as the vertex set and two vertices say x and y (x not equals to y) in R are adjacent if and only if their sum is zero-divisor. Genetic code is the blueprint for protein synthesis. In this paper we discuss total graph in the genetic code algebra. http://www.iaees.org/publications/journals/nb/articles/2022-12(1)/total-graph-in-genetic-code-algebra.pdf