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Network Biology, 2022, 12(4): 133-141
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Article

Evolutionary aspect of protein sequence network based on the 2D representation of amino acids

Sanjay Sharma, Birinchi Kumar Boruah, Tazid Ali
Department of Mathematics, Dibrugarh University, Assam, India 786004

Received 7 June 2022;Accepted 15 July 2022;Published online 16 August 2022;Published 1 December 2022
IAEES

Abstract
For the comparative analysis of proteins, their proper clustering, and evolutionary relationships require analysis of their sequences. We used a mathematical parameter termed a similar factor to create a similar degree matrix of ND6 protein sequences taken from eight different species in this paper. We built a network out of the matrix to analyze their evolutionary and similarity trends with each other. By observing the various centrality measures, the correlation between multiple centrality measures and different network parameter shows that our network is consistent with the known evolution fact of ND6 protein sequences.

Keywords amino acids;similar factor;similar degree matrix;characteristic vector;centrality measures;clustering coefficient.

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