Aparna Chaurasia Vikas Chaurasia Research Enthusiastic, India Department of Computer Applications, MHPGC, VBS Purvanchal University, India Network Biology ISSN 2220-8879 http://www.iaees.org/publications/journals/nb/online-version.asp 2023 13 1 1 16 International Academy of Ecology and Environmental Sciences Hong Kong 17 September 2022 25 October 2022 1 March 2023 heart disease feature selection SFS stacking model comparison model classifiers The exact forecast of heart disease is necessary to proficiently treat cardiovascular patients before a heart failure happens. Assuming we talk about AI techniques can be accomplished utilizing an ideal AI model with rich medical services information on heart diseases. To begin with, the feature extraction technique, gradient boosting-based sequential feature selection (GBSFS) is applied to separate the significant number of features (5, 7, 9, and 11) from coronary illness dataset to create important medical services information. The stacking model is prepared for coronary illness forecast. A comparison model is made between datasets with prominent features (5, 7, 9, and 11) as well as all features. The proposed framework is assessed with coronary illness information and contrasted and customary classifiers in view of feature elimination include determination strategies. The proposed framework acquires test accuracy of 98.78%, which is most noteworthy in marking model with 11-featuers and higher than existing frameworks. This outcome shows that our framework is more powerful for the expectation of coronary illness, in contrast with other cutting edge strategies. http://www.iaees.org/publications/journals/nb/articles/2023-13(1)/predict-heart-disease-using-machine-learning-classifiers.pdf