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Network Biology, 2025, 15(1): 15-23
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Article

Application of signed graph in amino acid network

Adil Akhtar1, Nasrin Irshad Hussain2
1Department of Mathematics, Golaghat Engineering College, Assam 785621, India
2Department of Computer Application, Sibsagar University, Assam 785665, India

Received 4 September 2024;Accepted 15 October 2024;Published online 20 October 2024;Published 1 March 2025
IAEES

Abstract
This article is aimed to construct a model related to protein structure and amino acids viz., Brandstein and Tooze's condition. To study Brandstein and Tooze's condition we have considered signed graph in amino acids. For this we have constructed a network structure, where the link is based on the one point mutation of codons of corresponding 20 different essential amino acids. To study this we have considered signed graph in amino acids and consider two cases. In the first case positive sign is assigned to an edge if both the amino acids are either hydrophobic or hydrophilic, otherwise negative sign is assigned. And in the second case positive sign is assigned to an edge if one amino acid is hydrophobic and the other is hydrophilic, otherwise negative sign is assigned.

Keywords amino acid;graph;chemical graph;signed graph.


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