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Proceedings of the International Academy of Ecology and Environmental Sciences, 2016, 6(1): 13-23
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Article

A cluster method for finding node sets / sub-networks based on between-node similarity in sets of adjacency nodes: with application in finding sub-networks in tumor pathways

WenJun Zhang1, Xin Li2
1School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China; International Academy of Ecology and Environmental Sciences, Hong Kong
2College of Plant Protection, Northwest A and F University, Yangling 712100, China; Yangling Institute of Modern Agricultural Standardization, Yangling 712100, China

Received 6 August 2015;Accepted 28 September 2015;Published online 1 March 2016
IAEES

Abstract
A network consists of node sets or sub-networks. In present study, a cluster method for finding node sets and sub-networks according to between-node similarity in sets of adjacency nodes was proposed. A typical example demonstrated that the method is highly effective. Sub-networks in tumor pathways are identified. Matlab codes of the method are presented.

Keywords node sets;sub-networks;cluster analysis;similarity;sets of adjacency nodes;tumor pathways.


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