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Network Pharmacology, 2022, 7(3-4): 5-12
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Article

Identifications of Aloe vera fractions and application as a cure for diseases

Eman Tawfik1, Mayar Medhat2
1Genetics and Genetic Engineering, Botany and Microbiology Department, Faculty of Science, Helwan University, Egypt
2Biotechnology Department, Faculty of Science, Helwan University, Egypt

Received 21 April 2022;Accepted 23 May 2022;Published online 25 May 2022;Published 1 December 2022
IAEES

Abstract
Many of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological activities include promotion of wound healing, antifungal activity, hypoglycemic or antidiabetic effects anti-inflammatory, anticancer, immunomodulatory and gastroprotective properties. There are several mechanisms which contribute to the immunological protection enjoyed by normal persons. Among these mechanisms the ingestion of bacteria and other potentially harmful agents by certain white blood cells and the formation of antibodies. Aloe gel contains substances which are active both in stimulating phagocytosis as well as stimulating the formation of antibodies. These effects include the potential of whole leaf or inner fillet gel liquid preparations of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation. In addition, important pharmaceutical applications such as the use of the dried A. vera gel powder as an excipient in sustained release pharmaceutical dosage forms were outlined.

Keywords Aloe vera;medicine plant;phenolics;flavonoids;LC-MS;psoriasis.


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